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This is an overview of the topics to be covered in the Purdue Summer boot camp on big data training for biomedical researchers.
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In this video we explain the concepts for searching DNA to find transcription factor binding sites. This includes a discussion of databases and tools as well as a demonstration of a simple tool…
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In this video we use IGV to visualize DNA-seq data. The demonstration uses date from the ENCODE project as well as BED file made from supplemental data in a published paper.
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This video provides an overview of the ENCODE project and tours through the ENCODE data portal.
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This video explains how Jupyter notebooks work and how to use them. It is an essential prelude to the BigTap On-line course.
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This video provides an overview of how to open, navigate, edit, save, restart, and close Jupyter notebooks for the BigTap on-line course.
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This is a brief overview of the four major course resources that students will use in the BigTap on-line course.
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This video provides an overview of tools that are available to understand the relationship between your deferentially expressed gene list and biological functions. Within the video are links to…
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This is a demonstration on how to use the desktop version of the the Gene Set Enrichment Analysis (aka GSEA) software to analyze genomics studies. GSEA links biological datasets to genesets of…
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This short video presents the content that will be taught and the skill reinforcing exercises that make up Unit 1 of the BigTap on-line course.
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The purpose of this video is to introduce three tools that can be used to understand candidate genes that are identified in omic analysis: BioGPS, Genecards, and Coremine
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Here we discuss the public databases and repositories that exist for genomic and other omic data. We'll focus on the Gene Expression Omnibus and show how a tool on that site - GEO2R - can be…
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This video describes the Affymetrix dataset that will be used during the hands-on exercise for the on-line course. In addition, it explains the analysis pipeline used in the original report of the…
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This video examines the special statistical challenges that exist for comparing samples from next generation sequencing (NGS) studies.
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This is an overview of the experiment we used for the RNA-seq analysis demonstration for the on-line course.
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Here we examine the tool of next generation sequencing (NGS) and how it can be used to measure the transcript profile of a biological sample (i.e. RNA-seq). Some basic concepts related to sequencing…
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