Search for tag: "genomics"

Transcription Factor Binding Site Prediction in DNA

In this video we explain the concepts for searching DNA to find transcription factor binding sites. This includes a discussion of databases and tools as well as a demonstration of a simple tool…

From  James C Fleet 783 plays 0  

Using IGV to visualize DNA-seq data

In this video we use IGV to visualize DNA-seq data. The demonstration uses date from the ENCODE project as well as BED file made from supplemental data in a published paper.

From  James C Fleet 241 plays 0  

Overview of ENCODE

This video provides an overview of the ENCODE project and tours through the ENCODE data portal.

From  James C Fleet 84 plays 0  

An introduction to IGV and its use for visualizaing RNA-seq data

This video has two purposes. First, it is an introduction to the Integrative Genomics Viewer (IGV). Afterwards we demonstrate how IGV can be used to visualize RNA-seq data.

From  James C Fleet 2,021 plays 0  

Unit 2 Overview for Online Course 2018

This video presents an overview of the topics that will be covered in Unit 2 of the BigTap online course.

From  James C Fleet 105 plays 0  

Hierarchical clustering and heatmaps in GenePattern

This video introduces the GenePattern repository of user friendly bioinformatic tools. Afterwards we use GenePattern to make and visualize hierarchical clusters and heatmaps using trancriptome data.

From  James C Fleet 334 plays 0  

Functional Assessment of genomic data 1-2-18

This video provides an overview of tools that are available to understand the relationship between your deferentially expressed gene list and biological functions. Within the video are links to…

From  James C Fleet 183 plays 0  

Gene Set Enrichment Analysis demonstration

This is a demonstration on how to use the desktop version of the the Gene Set Enrichment Analysis (aka GSEA) software to analyze genomics studies. GSEA links biological datasets to genesets of…

From  James C Fleet 729 plays 0  

Unit 1 online course introduction 1-2-18

This short video presents the content that will be taught and the skill reinforcing exercises that make up Unit 1 of the BigTap on-line course.

From  James C Fleet 216 plays 0  

Making sense of candidate genes identified in omics analysis

The purpose of this video is to introduce three tools that can be used to understand candidate genes that are identified in omic analysis: BioGPS, Genecards, and Coremine

From  James C Fleet 124 plays 0  

Public databases, GEO introduction, and GEO2R demonstration

Here we discuss the public databases and repositories that exist for genomic and other omic data. We'll focus on the Gene Expression Omnibus and show how a tool on that site - GEO2R - can be…

From  James C Fleet 551 plays 0  

Statistical Issues for differential gene expression using next generation sequencing data

This video examines the special statistical challenges that exist for comparing samples from next generation sequencing (NGS) studies.

From  James C Fleet 116 plays 0  

Next generation sequencing and RNA-seq analysis

Here we examine the tool of next generation sequencing (NGS) and how it can be used to measure the transcript profile of a biological sample (i.e. RNA-seq). Some basic concepts related to sequencing…

From  James C Fleet 223 plays 0  

DNA-seq dataset description for on-line course

This is a description of the experiment and paper that we used in our on-line course to demonstrate how to analyze a DNA-Seq study.

From  James C Fleet 66 plays 0  

DNA-seq applications overview

This video discusses the use of next generation sequencing (NGS) to study DNA. It focuses on the concepts important for understanding the protein-DNA interactions that control gene transcription and…

From  James C Fleet 115 plays 0  

Statistical Issues for differential gene expression using microarrays

Here we review some basic statistical principles for defining differences between treatment groups. We extend that to address the statistical challenge that comes from doing thousands of comparisons…

From  James C Fleet 174 plays 0